Peripheral Neuropathies Revealing Gougerot-Sjögren’s Syndrome: Description of 3 Cases

Introduction: Sjögren’s syndrome is an autoimmune epithelitis with various extraglandular signs, among which are neurological, a variable frequency according to studies. We report three cases of peripheral neuropathy revealing Gougerot-Sjögren’s syndrome, collected in the Neurology Department Fann University Hospital Dakar (Senegal). Observations: The first patient, aged 48 years, presented length-dependent sensitivomotor polyneuropathy associated retrobulbar optic neuritis, dry eyes and mouth noticed by patient for several years. second 28 was admitted hospital chronic generalized paresthesia context xerostomia xerophthalmia. results clinical examination electroeneuromyogram were favour pure sensory neuronopathy. third 32 years old female, history thyroidectomy acute inflammatory demyelinating (AIDP), who seen ascending flaccid tetraplegia facial diplegia, preceded diffuse paresthesia. diagnosis recurrence polyradiculonueropathy retained view rapidly increasing character deficit, hyperproteinorachy at lumbar puncture, signs demyelination ENMG. our patients established on basis 2016 ACR/EULAR criteria. Indeed, anti-SSA antibodies (Ro) positive 3 biopsy salivary glands showed stage 4 two others. Corticosteroid therapy immunosuppressive treatment resulted favourable evolution neurological general levels. Conclusion: exocrinopathy that may present neuropathy, precede be concomitant or occur during course disease.